News from Lifespan.io campaigns

Before I’m too late for the party, I’d like to let you know that Lifespan.io’s crowdfunding campaign AgeMeter for the development of a diagnostic system to measure functional human age has been extended by two weeks. Presently, 70% of the necessary funds have been collected, i.e. a little over 20.000 dollars out of 30.000. It would be great if yet this other campaign made it to its goal, so if you haven’t made your donation yet, please do—remember, there’s no such thing as a donation which is too small: Broadly speaking, as long as the amount you donate is a positive real number, it is much appreciated! The AgeMeter campaign will end on September 16, 2017.

Contextually, another Lifespan.io crowdfunding campaign has been launched: MouseAge, an AI project aimed at assessing ageing biomarkers in mice visually, using image recognition techniques. If successful, this approach could help speed up rejuvenation research and reduce animal suffering. I’ll let the researchers speak:

MouseAge ends on October 14, 2017. As always, please donate if you can, and do spread the word as far and wide as possible. Thanks!

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I don’t like this one tiny bit.

I’m not a biologist, you probably know that. I’m thinking about getting a degree in biology, but presently I have no competence to say what makes sense and what does not, biologically speaking. All I say on this website about what may or may not cure ageing is the word of experts of the field, which I merely repeat in a different fashion.

However, having studied natural sciences and having been around on the planet for long enough, I’ve learned to be skeptical about solutions that seem too easy. Especially when the silver bullet seems to have been discovered much too suddenly.

As you probably remember, BioViva has recently experimented a type of gene therapy against ageing on its own CEO Liz Parrish. The aim of the treatment was to lengthen her telomeres, and according to preliminary data, it worked. I care to emphasise the fact that this experiment had a sample size of one.

Dr. Bill Andrews, founder of Sierra Sciences and discoverer of telomerase, the enzyme used by cells to lenghten their own telomeres, has always been dead set on curing ageing—a very noble goal. Thing is, Sierra Sciences and BioViva have now teamed up and apparently launched a company called BioViva Fiji, unsurprisingly located on the homonymous island. They’re building a clinic where this treatment can be administered to arguably rich clients. The reason Fiji was chosen as the location of this clinic is that the Fiji equivalent of FDA seems to have much less strict regulations.

In a video that is not so new any more (I am a slow poster), Dr. Andrews announced the creation of BioViva Fiji and made some pretty bold statements, such as a cure for ageing to be expected “really, really soon.”

You certainly know how much I wish for ageing to be brought under medical control, so you would think I should be excited at the news. I’m not. Why?

This is sketchy as fuck. Bold claims about curing ageing—something most people on the planet probably still think to be nonsense—a private, expensive clinic on the other side of the world where regulations don’t matter as much as setting up medical businesses, and a miracle treatment coming from an experiment with sample size ONE that hasn’t even been fully monitored yet. I’m betting you anything most people’s scam indicator would go through the roof, irrespective of how effective the treatment actually is. This is the kind of stuff that gives the field a bad reputation, and if BioViva were to be wrong or if nasty side effects were to arise as a consequence of the treatment, shit would hit the fan for BioViva, and I fear the shockwave would be felt throughout the entire anti-ageing research field.

It seems awfully simple. Andrews seem to think telomerase/gene therapy is the silver bullet that will fully cure ageing, and while, I repeat, I am not qualified to say he’s wrong, it seems too damn easy. All age-related diseases would boil down to your telomeres getting too short? Is he saying that other age-related damange, like the seven categories of damage that the SENS platform is supposed to fix, are not really relevant? Or can they too be fixed with a shot of telomerase? (I hope he’s not saying that about cancer, because cancer may have 99 problems, but telomerase ain’t one.)

I’m sorry, but I don’t like this. It doesn’t come across as respectable scientists pushing research foward, but rather like a group of a bit too enthusiastic people who think they’ve already solved the general case of a problem because they have got a particular case sort of maybe working. I may be a boring traditionalist, but I still prefer the SENS approach, and I’m not talking only about their approach to defeating ageing, but also to doing science.